Efficiency of Bromelain-Enriched Enzyme Mixture (NexoBrid™) in the Treatment of Burn Wounds

نویسندگان

چکیده

Background: The use of bromelain for the removal eschar in deep burns is considered to be effective because it does not affect unaffected skin and leaves a clean dermis after use. main objective this study find out whether good alternative surgical debridement. In order achieve that, we aim evaluate its indications, limitations, safety measures. Methods: current was conducted on group 30 patients with burn lesions, aged 20 56 years, from which 15 underwent enzymatic debridement acted as control primary used. mixture enzymes enriched bromelain, meant dissolve eschar, provided by NexoBrid™. inclusion criteria were agreement manufacturer’s protocols, but application protocol slightly modified implement better intern assess efficiency. Results: Complete obtained 13 cases, 10 went through spontaneous healing 3 needed covered graft. other 2 partial associated coverage split-thickness graft same operation. results two groups assessed Vancouver Scar Scale. Conclusions: Even though early excision followed remains gold standard treatment burns, can provide series advantages when exclusion are respected. Bromelain an that provides speed, tissue selectivity, safety, less blood loss.

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ژورنال

عنوان ژورنال: Applied sciences

سال: 2021

ISSN: ['2076-3417']

DOI: https://doi.org/10.3390/app11178134